Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25823897 | 0.82 | KMT2A (0.36) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL20792485 | 0.73 | KMT2A (0.34) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL24420455 | 0.70 | DAO (0.40) | KMT2ACYP2C9MAPTMEN1GAA | |
| SCHEMBL25823734 | 0.69 | ALDH1A1 (0.47) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL9910660 | 0.67 | MAPK1 (0.44) | — | |
| SCHEMBL25826087 | 0.66 | CYP2C19 (0.40) | KMT2ACYP2C9MAPTMEN1CYP1A2 | |
| SCHEMBL25824824 | 0.66 | CYP2C19 (0.35) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL25823728 | 0.66 | KDM4E (0.56) | KMT2ACYP2C9MEN1HTTCYP2C19 | |
| SCHEMBL22873334 | 0.66 | TNKS (0.33) | TDP1 | |
| SCHEMBL12702585 | 0.66 | GRIA1 (0.39) | KMT2AMAPTMEN1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |