Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824824 | 0.82 | CYP2C19 (0.35) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL25823897 | 0.82 | KMT2A (0.36) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL25824691 | 0.72 | SMN1; SMN2 (0.49) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL22666437 | 0.71 | TK1 (0.49) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL23240428 | 0.70 | BRD4 (0.49) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL25824415 | 0.69 | DAO (0.37) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL23240661 | 0.68 | KMT2A (0.37) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL24420283 | 0.68 | KMT2A (0.37) | CYP2C19CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL22020875 | 0.67 | MAPK1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL25823728 | 0.67 | KDM4E (0.56) | CYP2C19CYP2C9KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |