Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 3/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25823735 | 0.82 | KMT2A (0.33) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL25824824 | 0.82 | CYP2C19 (0.35) | KMT2ACYP2C9MAPTSMN1; SMN2MEN1 | |
| SCHEMBL25826087 | 0.82 | CYP2C19 (0.40) | KMT2ACYP2C9MAPTSMN1; SMN2MEN1 | |
| SCHEMBL23240428 | 0.79 | BRD4 (0.49) | KMT2ACYP2C9BRD4MAPTSMN1; SMN2 | |
| SCHEMBL25823734 | 0.79 | ALDH1A1 (0.47) | KMT2ACYP2C9MAPTMEN1HTT | |
| SCHEMBL25823728 | 0.79 | KDM4E (0.56) | KMT2ACYP2C9BRD4MEN1HTT | |
| SCHEMBL23240661 | 0.78 | KMT2A (0.37) | KMT2ACYP2C9BRD4MAPTSMN1; SMN2 | |
| SCHEMBL24420283 | 0.78 | KMT2A (0.37) | KMT2ACYP2C9BRD4MAPTSMN1; SMN2 | |
| SCHEMBL25824691 | 0.75 | SMN1; SMN2 (0.49) | KMT2ACYP2C9BRD4MAPTSMN1; SMN2 | |
| SCHEMBL20792485 | 0.75 | KMT2A (0.34) | KMT2ACYP2C9MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |