Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871232 | 0.78 | GRIA1 (0.38) | DAOLMNAPOLBCYP2C9KMT2A | |
| SCHEMBL25823753 | 0.78 | TK1 (0.40) | DAOKDM4EHPGDCYP2C9KMT2A | |
| SCHEMBL27057530 | 0.77 | KDM4E (0.44) | KDM4ELMNACYP2C9KMT2AMAPT | |
| SCHEMBL21283135 | 0.75 | MAPK1 (0.33) | DAOTDP1TK1 | |
| SCHEMBL24420455 | 0.69 | DAO (0.40) | DAOHPGDTSHRCYP2C9KMT2A | |
| SCHEMBL25824402 | 0.68 | KMT2A (0.36) | KDM4ECYP2C9KMT2AMAPTHTT | |
| SCHEMBL20966271 | 0.67 | HTT (0.43) | KDM4ERECQLHTTGAA | |
| SCHEMBL6882444 | 0.67 | PYGM (0.61) | LMNAHPGDTSHRMAPTTK2 | |
| SCHEMBL13447776 | 0.67 | PYGM (0.61) | LMNAHPGDTSHRMAPTTK2 | |
| SCHEMBL9910660 | 0.66 | MAPK1 (0.44) | LMNAPOLBHPGDALDH1A1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |