SCHEMBL25823783

SCHEMBL25823783

Cc1noc2ccc3c(c12)CCCC(C)C3

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2A6 P11509 2/20 0.32
CYP2A13 Q16696 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25591601 0.83
SCHEMBL25823774 0.78 HCRTR1 (0.35) ALDH1A1LMNACYP2A6CYP2A13TSHR
SCHEMBL25815995 0.69 KDM4E (0.31) LMNASMN1; SMN2
SCHEMBL25816627 0.64 HTR2A (0.37) ALDH1A1
SCHEMBL19070853 0.63 CYP2A6 (0.42) ALDH1A1LMNASMN1; SMN2CYP2A6CYP2A13
SCHEMBL25595351 0.63 HRH1 (0.32) ALDH1A1LMNA
SCHEMBL25669745 0.63 CYP1A2 (0.41) ALDH1A1LMNAMAPT
SCHEMBL12315699 0.62 HTR1A (0.40) ALDH1A1SMN1; SMN2CYP2A6CYP2A13TSHR
SCHEMBL22910898 0.60 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL598666 0.60 CYP2A6 (0.46) ALDH1A1CYP2A6CYP2A13TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed