Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | USP9X | Q93008 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 4/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8277403 | 0.67 | DRD1 (0.39) | DRD1ADRA2ASLC9A1EEDSUZ12 | |
| SCHEMBL17190972 | 0.66 | DRD1 (0.46) | HTR2ADRD1SLC9A1MTNR1AEED | |
| SCHEMBL25599898 | 0.65 | NOTUM (0.33) | HTR2AALDH1A1 | |
| SCHEMBL25669745 | 0.65 | CYP1A2 (0.41) | DRD1ALDH1A1CYP1A2 | |
| SCHEMBL11996624 | 0.65 | MAOA (0.41) | HTR2AHTR2CHTR2BDRD1ADRA2A | |
| SCHEMBL25823783 | 0.64 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL5541102 | 0.62 | MAOA (0.35) | HTR2AHTR2CHTR2BMTNR1ACDK1 | |
| SCHEMBL10158533 | 0.62 | HTR2C (0.35) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL21603512 | 0.62 | MAOA (0.39) | HTR2AHTR2CHTR2BSLC9A1KIF11 | |
| SCHEMBL2056488 | 0.62 | EED (0.38) | HTR2AHTR2CHTR2BEEDSUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |