SCHEMBL25824039

SCHEMBL25824039

CC[C@H]1O[C@@H](n2cccnc2=O)C(OC(=O)c2ccccc2)[C@H]1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDA P32320 2/20 0.44
MAPT P10636 1/20 0.44
POLB P06746 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
GAPDH P04406 2/20 0.39
P2RX3 P56373 1/20 0.37
P2RX4 Q99571 1/20 0.37
P2RX2 Q9UBL9 1/20 0.37
ALDH1A1 P00352 2/20 0.37
LGALS9 O00182 1/20 0.36
LGALS1 P09382 1/20 0.36
LGALS3 P17931 1/20 0.36
LGALS7; LGALS7B P47929 1/20 0.36
P2RY11 Q96G91 1/20 0.36
P2RY6 Q15077 2/20 0.35
P2RY14 Q15391 2/20 0.35
HTT P42858 1/20 0.35
NT5E P21589 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27055211 1.00 CDA (0.44) CDAMAPTPOLBMEN1KMT2A
SCHEMBL17999172 0.92 MEN1 (0.46) CDAMAPTPOLBMEN1KMT2A
SCHEMBL26554463 0.86 GAPDH (0.41) POLBMEN1KMT2AUSP2GAPDH
SCHEMBL10024708 0.84 ALDH1A1 (0.47) POLBMEN1KMT2AUSP2GAPDH
SCHEMBL16904883 0.82 POLB (0.57) POLBMEN1KMT2AUSP2GAPDH
SCHEMBL23240641 0.82 POLB (0.60) CDAMAPTPOLBMEN1KMT2A
SCHEMBL21586638 0.82 POLB (0.60) CDAMAPTPOLBMEN1KMT2A
SCHEMBL17968547 0.82 POLB (0.60) CDAMAPTPOLBMEN1KMT2A
SCHEMBL12746639 0.82 POLB (0.48) POLBMEN1KMT2AUSP2GAPDH
SCHEMBL26554384 0.81 MEN1 (0.41) POLBMEN1KMT2AUSP2GAPDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220384-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-07-13 US disclosed