Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.43 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024704 | 0.86 | LMNA (0.52) | ALDH1A1DNMT1HTTGMNNLMNA | |
| SCHEMBL14549613 | 0.86 | LMNA (0.52) | ALDH1A1DNMT1HTTGMNNLMNA | |
| SCHEMBL26808476 | 0.84 | P2RY11 (0.48) | ALDH1A1LMNATP53P2RX3P2RX4 | |
| SCHEMBL17464581 | 0.84 | P2RY11 (0.48) | ALDH1A1LMNATP53P2RX3P2RX4 | |
| SCHEMBL15837358 | 0.84 | P2RY11 (0.48) | ALDH1A1LMNATP53P2RX3P2RX4 | |
| SCHEMBL27055211 | 0.84 | CDA (0.44) | ALDH1A1HTTP2RX3P2RX4P2RX2 | |
| SCHEMBL25824039 | 0.84 | CDA (0.44) | ALDH1A1HTTP2RX3P2RX4P2RX2 | |
| SCHEMBL784542 | 0.83 | TAS1R3 (0.55) | P2RX3P2RX4P2RX2P2RY11TAS1R3 | |
| SCHEMBL26808474 | 0.83 | TAS1R3 (0.55) | P2RX3P2RX4P2RX2P2RY11TAS1R3 | |
| SCHEMBL13376162 | 0.83 | MEN1 (0.58) | ALDH1A1DNMT1HTTGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029181-A1 | SYNTHESIS OF 5-AZACYTIDINE | PHARMION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-8058424-B2 | Synthesis of 5-azacytidine | PHARMION LLC (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110092694-A1 | SYNTHESIS OF 5-AZACYTIDINE | PHARMION LLC | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092694-A1 | SYNTHESIS OF 5-AZACYTIDINE | TYMS, DNMT1, TET1 | ALDH1A1 2154/4885DNMT1 2/4885HTT 2279/4885 |
| US-20120029181-A1 | SYNTHESIS OF 5-AZACYTIDINE | TYMS, DNMT1, TET1 | ALDH1A1 2154/4885DNMT1 2/4885HTT 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.