Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 2/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.35 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27055215 | 1.00 | MEN1 (0.41) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL23215313 | 0.84 | POLB (0.59) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL23240642 | 0.84 | POLB (0.59) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL25605657 | 0.79 | BCHE (0.37) | MEN1KMT2APOLBUSP2GAA | |
| SCHEMBL27055213 | 0.79 | MEN1 (0.40) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL25824040 | 0.79 | MEN1 (0.40) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL26554384 | 0.78 | MEN1 (0.41) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL26554463 | 0.76 | GAPDH (0.41) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL27055211 | 0.76 | CDA (0.44) | MEN1KMT2APOLBUSP2GAPDH | |
| SCHEMBL25824039 | 0.76 | CDA (0.44) | MEN1KMT2APOLBUSP2GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |