Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 4/20 | 0.47 |
| ▸ | TK1 | P04183 | 2/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240762 | 0.87 | CDA (0.58) | CDATK1TK2LMNASMN1; SMN2 | |
| SCHEMBL27054478 | 0.87 | CDA (0.58) | CDATK1TK2LMNASMN1; SMN2 | |
| SCHEMBL172249 | 0.87 | CDA (0.58) | CDATK1TK2LMNASMN1; SMN2 | |
| SCHEMBL11260242 | 0.84 | CDA (0.63) | CDATK1TK2LMNASMN1; SMN2 | |
| SCHEMBL24420619 | 0.83 | CDA (0.41) | CDASMN1; SMN2 | |
| SCHEMBL25824071 | 0.79 | CDA (0.38) | CDA | |
| SCHEMBL27054121 | 0.71 | CDA (0.41) | CDASMN1; SMN2 | |
| SCHEMBL27058587 | 0.71 | CDA (0.41) | CDASMN1; SMN2 | |
| SCHEMBL14503531 | 0.71 | TK1 (0.35) | TK1TK2LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17599181 | 0.69 | CDA (0.45) | CDASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |