Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.37 |
| ▸ | PSMC4 | P43686 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240669 | 0.84 | BRD4 (0.53) | BRD4NT5C2NT5ECSF1RTDP1 | |
| SCHEMBL25823819 | 0.83 | KDM4E (0.42) | HTTPOLBNPC1RAB9ATP53 | |
| SCHEMBL18349587 | 0.72 | NPC1 (0.51) | BRD4HTTADORA3POLBPKM | |
| SCHEMBL12942226 | 0.72 | ABL1 (0.47) | NPC1RAB9AEGFRAURKB | |
| SCHEMBL3784641 | 0.71 | MAPK14 (0.55) | BRD4POLBPKMNPC1RAB9A | |
| SCHEMBL29673051 | 0.71 | ADK (0.49) | TDP1HTTADORA3NPC1RAB9A | |
| SCHEMBL23216968 | 0.71 | ADK (0.49) | TDP1HTTADORA3NPC1RAB9A | |
| SCHEMBL13020230 | 0.70 | VCP (0.53) | BRD4HTTADORA3POLBPKM | |
| SCHEMBL23215743 | 0.69 | ADK (0.46) | BRD4CSF1RADORA3POLBADORA2A | |
| SCHEMBL29673049 | 0.69 | ADK (0.46) | BRD4CSF1RADORA3POLBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |