Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824559 | 0.83 | BRD4 (0.50) | HTTNPC1RAB9APOLBVCP | |
| SCHEMBL25823816 | 0.74 | TLR7 (0.46) | KDM4EALDH1A1HTTRETKDR | |
| SCHEMBL26779045 | 0.69 | SLC6A5 (0.42) | KDM4EALDH1A1HTTRXFP1L3MBTL1 | |
| SCHEMBL26779026 | 0.69 | CDK1 (0.37) | ALDH1A1FEN1RXFP1BRAFMEN1 | |
| SCHEMBL26779074 | 0.68 | CDK1 (0.41) | KDM4EALDH1A1HTTRXFP1L3MBTL1 | |
| SCHEMBL3619552 | 0.67 | HIF1A (0.43) | SMN1; SMN2 | |
| SCHEMBL27054264 | 0.66 | ADORA2A (0.43) | ALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL26800760 | 0.66 | CDK1 (0.58) | KDM4EALDH1A1HTTRXFP1L3MBTL1 | |
| SCHEMBL23240669 | 0.65 | BRD4 (0.53) | ALDH1A1HTTNPC1RAB9ACYP2C9 | |
| SCHEMBL16513126 | 0.65 | BRAF (0.45) | KDM4EL3MBTL1BRAFNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |