Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568925 | 0.91 | MAOB (0.53) | TSHRMAOBL3MBTL1TDP1PLA2G4B | |
| SCHEMBL4568922 | 0.89 | MAOB (0.51) | TSHRMAOBL3MBTL1TDP1PLA2G4B | |
| SCHEMBL4568917 | 0.88 | MAOB (0.53) | TSHRMAOBL3MBTL1TDP1PLA2G4B | |
| SCHEMBL3968967 | 0.85 | CYP4F2 (0.51) | MAOBL3MBTL1CYP2D6TDP1PLA2G4B | |
| SCHEMBL2207600 | 0.84 | TAAR1 (0.55) | MAOBL3MBTL1TDP1KCNA3 | |
| SCHEMBL29818962 | 0.84 | TAAR1 (0.55) | MAOBL3MBTL1TDP1KCNA3 | |
| SCHEMBL4568870 | 0.84 | TDP1 (0.52) | TSHRL3MBTL1CYP2D6TDP1PLA2G4B | |
| SCHEMBL13881714 | 0.84 | HTR1B (0.58) | MAOBALDH1A1L3MBTL1TDP1KDM4E | |
| SCHEMBL4249052 | 0.84 | TDP1 (0.52) | TSHRL3MBTL1CYP2D6TDP1PLA2G4B | |
| SCHEMBL13434095 | 0.83 | MAOB (0.73) | MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TSHR 2971/4885MAOB 332/4885ALDH1A1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.