SCHEMBL25824773

SCHEMBL25824773

Brc1c(-c2ccccc2)oc2ccc(-c3ccccc3)cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.47
PLA2G4A P47712 3/20 0.47
ADORA3 P0DMS8 2/20 0.43
PGR P06401 1/20 0.41
KDM4E B2RXH2 5/20 0.41
MAPT P10636 4/20 0.41
RAB9A P51151 2/20 0.41
PLA2G10 O15496 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825859 0.81 KMT2A (0.53) PLA2G2APLA2G4AADORA3KDM4EMAPT
SCHEMBL6826170 0.79 ALDH1A1 (0.64) KDM4EMAPTRAB9AMEN1KMT2A
SCHEMBL21151721 0.78 PLA2G2A (0.58) PLA2G2APLA2G4AADORA3PGRKDM4E
SCHEMBL1784272 0.78 PLA2G2A (0.58) PLA2G2APLA2G4AADORA3PGRKDM4E
SCHEMBL14295997 0.78 PLA2G2A (0.58) PLA2G2APLA2G4AADORA3PGRKDM4E
SCHEMBL30704823 0.76 GABRP (0.57) PLA2G2APLA2G4APGRMAPTRAB9A
SCHEMBL14679598 0.76 GABRP (0.57) PLA2G2APLA2G4APGRMAPTRAB9A
SCHEMBL1635672 0.75 PLA2G2A (0.55) PLA2G2APLA2G4AADORA3PGRKDM4E
SCHEMBL9889816 0.75 PLA2G2A (0.55) PLA2G2APLA2G4APGRKDM4EMAPT
SCHEMBL1635801 0.75 PLA2G2A (0.55) PLA2G2APLA2G4AADORA3PGRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132488-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-13 WO disclosed