Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324795 | 0.77 | HSD11B1 (0.53) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL15200519 | 0.75 | HSD11B1 (0.47) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL26700772 | 0.74 | HSD11B1 (0.46) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL25389619 | 0.72 | HSD11B1 (0.44) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22855889 | 0.71 | HTT (0.46) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL24276456 | 0.71 | CHRNB2 (0.48) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25810400 | 0.69 | HSD11B1 (0.66) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL17177244 | 0.68 | GRM5 (0.49) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL15199123 | 0.68 | HSD11B1 (0.41) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25388586 | 0.68 | HSD11B1 (0.41) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |