Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25389619 | 0.98 | HSD11B1 (0.44) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL21324795 | 0.82 | HSD11B1 (0.53) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL15200519 | 0.80 | HSD11B1 (0.47) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL29809245 | 0.78 | HPGD (0.50) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22855889 | 0.75 | HTT (0.46) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL24276456 | 0.75 | CHRNB2 (0.48) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25810400 | 0.74 | HSD11B1 (0.66) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25824960 | 0.74 | HSD11B1 (0.42) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL17177244 | 0.72 | GRM5 (0.49) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25388586 | 0.72 | HSD11B1 (0.41) | HSD11B1HPGDCHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348424-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | SCHRÖDINGER, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348424-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | APC, RCC2, CDC37 | HSD11B1 1791/4885HPGD 95/4885CHRNB2 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.