SCHEMBL25825832 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	SIGMAR1	Q99720	2/20	0.46

▸	MEN1	O00255	2/20	0.41

▸	KMT2A	Q03164	2/20	0.41

▸	TSHR	P16473	2/20	0.41

▸	GAA	P10253	1/20	0.41

▸	CYP2D6	P10635	6/20	0.41

▸	HDAC11	Q96DB2	1/20	0.40

▸	USP2	O75604	1/20	0.40

▸	CYP3A4	P08684	1/20	0.40

▸	ALDH1A1	P00352	1/20	0.38

▸	MC4R	P32245	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21326761	0.75	SIGMAR1 (0.49)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL8892977	0.72	GAA (0.59)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL11704797	0.68	BCL2L1 (0.46)	MEN1KMT2ATSHRUSP2CYP3A4
SCHEMBL23051658	0.68	CYP2D6 (0.48)	MEN1KMT2ATSHRGAACYP2D6
SCHEMBL23727894	0.68	SIGMAR1 (0.54)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL3464617	0.68	CYP2D6 (0.61)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL31230946	0.68	CYP2D6 (0.61)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL8894586	0.67	FUCA1 (0.51)	SIGMAR1MEN1KMT2ATSHRGAA
SCHEMBL538679	0.67	SIGMAR1 (0.82)	SIGMAR1MEN1KMT2ATSHRCYP2D6
SCHEMBL21326942	0.67	SIGMAR1 (0.53)	SIGMAR1MEN1KMT2AGAACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023125944-A1	COMPOUND CONTAINING HETEROCYCLIC RING	正大天晴药业集团股份有限公司	2023-07-06	—	—	WO	disclosed