Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820161 | 0.81 | HRH4 (0.51) | HRH4ADRB1ADRB2NCF1TGFBR1 | |
| SCHEMBL25820067 | 0.72 | GABRA1 (0.41) | — | |
| SCHEMBL14341117 | 0.71 | CHRNB2 (0.54) | CHRNB2CHRNA4HRH4ADRB1ADRB2 | |
| SCHEMBL4355823 | 0.70 | CHRNB2 (0.89) | CHRNB2CHRNA4KDM4EADRB1 | |
| SCHEMBL30020071 | 0.70 | CHRNB2 (0.89) | CHRNB2CHRNA4KDM4EADRB1 | |
| SCHEMBL24721906 | 0.70 | GABRA1 (0.39) | — | |
| SCHEMBL25820104 | 0.69 | IP6K1 (0.48) | KDM4EHRH4 | |
| SCHEMBL25820106 | 0.69 | IP6K1 (0.45) | KDM4EHRH4 | |
| Hydrochloric Acid SCHEMBL4057198 | 0.69 | CHRNB2 (0.86) | CHRNB2CHRNA4KDM4EADRB1 | |
| SCHEMBL28244687 | 0.69 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EADRB2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MET 1336/4885CHRNB2 4627/4885CHRNA4 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.