Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067375 | 0.75 | SIGMAR1 (0.48) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL24037260 | 0.74 | PDK1 (0.50) | PDK1 | |
| SCHEMBL3818437 | 0.72 | — | — | |
| SCHEMBL4550370 | 0.72 | SIGMAR1 (0.56) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL11962148 | 0.72 | SIGMAR1 (0.56) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL24177268 | 0.72 | GLB1 (0.38) | — | |
| SCHEMBL12125120 | 0.72 | SIGMAR1 (0.56) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL12125047 | 0.72 | SIGMAR1 (0.56) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL1564250 | 0.71 | SIGMAR1 (0.55) | PDK1SIGMAR1EBPKDM4EHTT | |
| SCHEMBL296049 | 0.71 | SIGMAR1 (0.55) | PDK1SIGMAR1EBPKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | PDK1 79/4885SIGMAR1 3212/4885EBP 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.