Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490661 | 0.89 | ABCB1 (0.51) | ABCB1ABCG2CTSGCMA1ALDH1A1 | |
| SCHEMBL25826919 | 0.82 | ALOX5 (0.53) | ALDH1A1ALOX5HPGD | |
| SCHEMBL490312 | 0.80 | ALOX5 (0.62) | ABCB1ABCG2CTSGCMA1ALOX5 | |
| SCHEMBL490311 | 0.80 | ALOX5 (0.47) | ABCB1ABCG2ALOX5KDM4E | |
| SCHEMBL490447 | 0.79 | POLB (0.47) | ALDH1A1ALOX5KDM4EHPGD | |
| SCHEMBL490982 | 0.76 | ALOX5 (0.48) | ALDH1A1ALOX5KDM4EHPGD | |
| SCHEMBL29232860 | 0.75 | TSHR (0.58) | ALDH1A1HPGD | |
| SCHEMBL490595 | 0.75 | ALOX5 (0.47) | ALOX5KDM4E | |
| SCHEMBL490577 | 0.75 | ALOX5 (0.47) | ALOX5KDM4E | |
| SCHEMBL8875136 | 0.75 | PTGES (0.58) | ALOX5PTGESPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |