Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490146 | 0.88 | ALOX5 (0.54) | ALOX5KMT2AG6PDALDH1A1LMNA | |
| SCHEMBL491167 | 0.83 | ALOX5 (0.51) | ALOX5KMT2AG6PDALDH1A1LMNA | |
| SCHEMBL25826288 | 0.82 | ABCB1 (0.50) | ALOX5ALDH1A1HPGD | |
| SCHEMBL491168 | 0.79 | ALOX5 (0.81) | ALOX5KMT2AALDH1A1 | |
| SCHEMBL490973 | 0.77 | ALOX5 (0.47) | ALOX5KMT2AG6PDALDH1A1LMNA | |
| SCHEMBL16672966 | 0.76 | HCAR2 (0.49) | ALOX5ALDH1A1LMNAHPGDAKR1B10 | |
| SCHEMBL38661412 | 0.76 | KMT2A (0.55) | KMT2AHPGD | |
| SCHEMBL490644 | 0.76 | ALOX5 (0.46) | ALOX5KMT2ATTRAKR1B10AKR1B1 | |
| SCHEMBL490982 | 0.75 | ALOX5 (0.48) | ALOX5KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL490927 | 0.75 | LDHA (0.65) | ALOX5KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |