SCHEMBL25826362

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12362963	0.84	CYP3A4 (0.52)	CYP17A1CYP19A1CYP11B1CYP11B2ALDH1A1
	SCHEMBL25826381	0.81	PIK3CB (0.38)	GAARAB9AUHRF1NOS3NOS1
	SCHEMBL27323925	0.80	LOXL2 (0.44)	CYP17A1CYP19A1CYP11B1CYP11B2CYP3A4
	SCHEMBL22604676	0.79	UHRF1 (0.50)	CYP3A4KDM4EUHRF1KCNQ2FLT1
	SCHEMBL25826364	0.79	TSHR (0.50)	GAAALDH1A1CYP3A4MAPTMEN1
	SCHEMBL295465	0.78	CYP3A4 (0.61)	CYP17A1CYP19A1CYP11B1CYP11B2GAA
	SCHEMBL29799746	0.78	CYP3A4 (0.61)	CYP17A1CYP19A1CYP11B1CYP11B2GAA
	SCHEMBL11221372	0.77	CYP17A1 (0.76)	CYP17A1CYP19A1CYP11B1CYP11B2GAA
	SCHEMBL20756914	0.77	UHRF1 (0.46)	CYP17A1CYP19A1CYP11B1CYP11B2ALDH1A1
	SCHEMBL25826448	0.77	UHRF1 (0.36)	UHRF1NOS3NOS1NOS2KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.