Sugi Predict

Sugi Predict / Compounds / SCHEMBL295465

SCHEMBL295465

SCHEMBL295465

Nc1ccc(Cc2ccc(N)c(N)c2)cc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 5/20 0.61
▸ GAA P10253 3/20 0.61
▸ MEN1 O00255 2/20 0.61
▸ KMT2A Q03164 2/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ POLB P06746 1/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ ALDH1A1 P00352 5/20 0.54
▸ CDC25B P30305 1/20 0.52
▸ CASP6 P55212 1/20 0.52
▸ RCE1 Q9Y256 1/20 0.52
▸ CYP17A1 P05093 1/20 0.52
▸ CYP19A1 P11511 1/20 0.52
▸ CYP11B1 P15538 1/20 0.52
▸ CYP11B2 P19099 1/20 0.52
▸ TDP1 Q9NUW8 4/20 0.48
▸ TSHR P16473 3/20 0.48
▸ ALOX15 P16050 4/20 0.45
▸ HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29799746 1.00 CYP3A4 (0.61) CYP3A4GAAMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL1600194 0.97 CYP3A4 (0.58) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL349528 0.90 ALDH1A1 (0.67) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL3187102 0.88 CALM1 (0.55) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL12633800 0.86 GAA (0.54) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL13964420 0.86 ALDH1A1 (0.48) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL11221372 0.84 CYP17A1 (0.76) CYP3A4GAAMEN1KMT2AKDM4E
SCHEMBL1599764 0.84 CYP19A1 (0.53) CYP3A4GAAMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL9659862 0.84 CYP3A4 (0.57) CYP3A4GAAMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL9661148 0.84 CYP3A4 (0.54) CYP3A4GAAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111971119-B Heterogeneous catalyst for carbamate synthesis 科思创知识产权两合公司 2023-12-08 — — CN claimed
US-11406964-B2 Heterogeneous catalysts for the synthesis of carbamates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-08-09 — — US claimed
CN-110650944-B Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2022-07-19 — — CN claimed
EP-3850698-A2 LOW PERMEABILITY POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES University of South Carolina (US) 2021-07-21 — — EP claimed
EP-3625210-B1 SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-06-23 — — EP claimed
US-20210053031-A1 HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-02-25 — — US claimed
EP-3774028-A1 HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES Covestro Intellectual Property GmbH & Co. KG (DE) 2021-02-17 — — EP claimed
CN-111971119-A Heterogeneous catalyst for carbamate synthesis 科思创知识产权两合公司 2020-11-20 — — CN claimed
CN-105229015-B Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates 科思创德国股份公司 2020-11-03 — — CN claimed
US-10807084-B2 Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines COVESTRO DEUTSCHLAND AG (DE) 2020-10-20 — — US claimed
US-5443859-A Reacting tetracarboxylic acid dianhydride, aromatic diamine, optionally polyamine, to form polyamic acid, forming film, imidizing to form polyimide, carbonizing in inert gas or vacuum to form carbon film with specifed properties TOHO RAYON CO., LTD. (JP) 1995-08-22 — — US claimed
EP-0387381-A1 Process for producing unsaturated dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1990-09-19 — — EP claimed
US-4427802-A POLYEPOXIDES HEXCEL CORPORATION (US) 1984-01-24 — — US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 — — US claimed
EP-0071197-A1 Heterocyclic multifunctional amine adducts and curable compositions containing the same HEXCEL CORPORATION (US) 1983-02-09 — — EP claimed
US-4253979-A HAVING GOOD HIGH TEMPERATURE PROPERTIES EXXON RESEARCH & ENGINEERING CO. (US) 1981-03-03 — — US claimed
US-4250322-A Oligourethanacrylates and methods for their manufacture ALTSHULER JUDIF M (SU) 1981-02-10 — — US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 — — US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 — — US claimed
US-4045414-A New di-substituted meta-terphenyl compounds and resulting polymers INSTITUT FRANCAIS DU PETROLE (FR) 1977-08-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210053031-A1 HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES SCO2, CDYL, PYM1 CYP3A4 1682/4885GAA 617/4885MEN1 2958/4885
US-11406964-B2 Heterogeneous catalysts for the synthesis of carbamates SCO2, CDYL, PYM1 CYP3A4 1682/4885GAA 617/4885MEN1 2958/4885
US-10807084-B2 Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines CDYL, ZYX, CXXC4 CYP3A4 1141/4885GAA 1532/4885MEN1 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.