Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826364 | 0.81 | TSHR (0.50) | SMN1; SMN2MAPTLMNARECQLMEN1 | |
| SCHEMBL25826450 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTLMNARECQLMEN1 | |
| SCHEMBL12727962 | 0.77 | POLB (0.63) | SMN1; SMN2MAPTMEN1HTTKMT2A | |
| SCHEMBL25826366 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2MAPTHTTKMT2APOLB | |
| SCHEMBL25826451 | 0.72 | MEN1 (0.38) | SMN1; SMN2MAPTLMNARECQLMEN1 | |
| SCHEMBL12240368 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL25786904 | 0.71 | HPGD (0.41) | SMN1; SMN2MAPTCYP2C9CYP2C19GAA | |
| SCHEMBL2255705 | 0.70 | PKM (0.40) | SMN1; SMN2MAPTGAANPSR1POLB | |
| SCHEMBL25826381 | 0.69 | PIK3CB (0.38) | GAAKCNQ2UHRF1 | |
| SCHEMBL19335823 | 0.68 | UHRF1 (0.39) | CYP3A4KCNQ2TSHRUHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | SMN1; SMN2 2070/4885MAPT 3999/4885LMNA 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.