Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826336 | 0.81 | TSHR (0.50) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL25826396 | 0.77 | HPGD (0.53) | ALDH1A1RAB9ASMN1; SMN2MAPTCDK2 | |
| SCHEMBL28487623 | 0.76 | L3MBTL1 (0.58) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL23410840 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29898984 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27273411 | 0.76 | LMNA (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL26310185 | 0.75 | HDAC3 (0.37) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL26310066 | 0.74 | ROCK1 (0.58) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL26310311 | 0.73 | ROCK1 (0.47) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL25826365 | 0.72 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ALDH1A1 4541/4885HDAC3 171/4885HDAC1 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.