Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316586 | 0.81 | HPGD (0.66) | TP53EPHX1SMN1; SMN2TGM2ALDH1A1 | |
| SCHEMBL3073181 | 0.80 | EPHX1 (0.52) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL11018412 | 0.78 | TP53 (0.56) | EPHX2TP53EPHX1TSHRCDK9 | |
| Benzene SCHEMBL28162617 | 0.78 | EPHX2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL57554 | 0.78 | SMN1; SMN2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| Diphenylurea SCHEMBL133103 | 0.78 | SMN1; SMN2 (1.00) | EPHX2TP53EPHX1TSHRCDK9 | |
| Benzene SCHEMBL28977956 | 0.78 | SMN1; SMN2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL7634 | 0.78 | EPHX2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL11306562 | 0.77 | EPHX2 (0.54) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL11353365 | 0.76 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920242-A | Preparation method of high-capacity graphite composite material | 格龙新材料科技(常州)有限公司 | 2022-08-19 | — | — | CN | claimed |
| US-20220120735-A1 | Testing Methods for Determination of T2R Phenotype and Applications Thereof | Phenomune, LLC | 2022-04-21 | — | — | US | claimed |
| WO-2022081729-A1 | TESTING METHODS FOR DETERMINATION OF T2R PHENOTYPE AND APPLICATIONS THEREOF | Phenomune, LLC (US) | 2022-04-21 | — | — | WO | claimed |
| CN-110849990-A | Method for detecting veterinary drug residues in animal-derived food and application thereof | 中国肉类食品综合研究中心 | 2020-02-28 | — | — | CN | claimed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| EP-1758849-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | Novartis AG (CH) | 2007-03-07 | — | — | EP | claimed |
| WO-2005121075-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2005-12-22 | — | — | WO | claimed |
| US-20030050248-A1 | Novel amino acid and peptide inhibitors of Staphylococcus virulence | PANORAMA RESEARCH, INC. | 2003-03-13 | — | — | US | claimed |
| EP-1261362-A2 | NOVEL AMINO ACID AND PEPTIDE INHIBITORS OF STAPHYLOCOCCUS VIRULENCE | Intermune, Inc. (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2001058471-A2 | NOVEL AMINO ACID AND PEPTIDE INHIBITORS OF STAPHYLOCOCCUS VIRULENCE | INTERMUNE, INC. (US) | 2001-08-16 | — | — | WO | claimed |
| EP-0314505-B1 | Herbicidal pyridine sulfonylureas | DU PONT (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0271208-B1 | HERBICIDAL PYRIDINE N-OXIDE SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0192489-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-10 | — | — | EP | claimed |
| EP-0192489-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-27 | — | — | EP | claimed |
| EP-0165003-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-18 | — | — | EP | claimed |
| US-4105838-A | LAYERS OF METAL COMPLEX WITH ORGANIC COMPOUND OR DYE ON REACTION VESSEL SURFACES, ANTISCALING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1978-08-08 | — | — | US | claimed |
| JP-61161201-A | — | — | None | — | — | JP | disclosed |
| JP-56115704-A | — | — | None | — | — | JP | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4028394-A | Antibacterial and fungicidal S-phenylthiocarbamates | R. T. VANDERBILT COMPANY, INC. (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | MB, ACHE, ADORA2B | EPHX2 1208/4885TP53 3970/4885EPHX1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.