Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099258 | 0.94 | SLC6A5 (0.52) | SLC6A5NAAADNM1CNR1CNR2 | |
| SCHEMBL20099238 | 0.92 | NAAA (0.47) | NAAADNM1SELPCNR1CNR2 | |
| SCHEMBL16217942 | 0.87 | SLC6A5 (0.40) | SLC6A5CNR1CNR2HRH3ALDH1A1 | |
| SCHEMBL23898968 | 0.85 | CD40 (0.46) | SLC6A5DNM1CNR1CNR2FAAH | |
| SCHEMBL24894033 | 0.85 | CASP2 (0.58) | SLC6A5NAAADNM1CNR1CNR2 | |
| SCHEMBL15592308 | 0.84 | SLC6A5 (0.42) | SLC6A5DNM1CNR1CNR2FAAH | |
| SCHEMBL22021431 | 0.84 | SLC6A5 (0.46) | SLC6A5NAAADNM1CNR1CNR2 | |
| SCHEMBL15592334 | 0.84 | RECQL (0.41) | SLC6A5FAAHHPGD | |
| SCHEMBL25826797 | 0.83 | CD40 (0.40) | SLC6A5 | |
| SCHEMBL24872398 | 0.83 | CD40 (0.43) | SLC6A5DNM1FAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957504-B2 | Compositions and methods for modulating apolipoprotein (a) expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |