SCHEMBL25827400

SCHEMBL25827400

Cc1cc(-n2ncc(=O)[nH]c2=O)cc(Cl)c1Oc1ccc(O)cc1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 19/20 0.66
THRA P10827 3/20 0.56
NPBWR1 P48145 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6213829 0.93 THRB (0.64) THRBTHRA
SCHEMBL6214724 0.90 THRB (0.62) THRBTHRANPBWR1
SCHEMBL24781755 0.84 THRB (0.63) THRBTHRA
SCHEMBL6219582 0.84 NPBWR1 (0.59) THRBTHRANPBWR1
SCHEMBL6218203 0.81 THRB (0.98) THRBTHRA
SCHEMBL9503278 0.81 THRB (0.59) THRBTHRA
SCHEMBL6216382 0.80 THRB (0.98) THRBTHRA
SCHEMBL6217148 0.80 THRB (0.76) THRBTHRA
SCHEMBL6217002 0.80 THRB (0.76) THRBTHRA
SCHEMBL6217927 0.80 THRB (1.00) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4201927-A1 CYANOTRIAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Chengdu Fanxi Biopharma Co., Ltd. (CN) 2023-06-28 EP disclosed