Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2584419 | 0.99 | MAOB (0.42) | MAOBADAM17KDM1ABCHETACR1 | |
| SCHEMBL8237041 | 0.85 | OPRM1 (0.46) | MAOBADAM17KDM1AHTR1ADRD1 | |
| SCHEMBL12168269 | 0.85 | OPRM1 (0.46) | MAOBADAM17KDM1AHTR1ADRD1 | |
| Hydrochloric Acid SCHEMBL2579713 | 0.78 | TACR1 (0.47) | MAOBADAM17BCHETACR1HTR1A | |
| Hydrochloric Acid SCHEMBL2586592 | 0.74 | LTA4H (0.46) | — | |
| Hydrochloric Acid SCHEMBL2577021 | 0.73 | OPRM1 (0.56) | — | |
| Ethane SCHEMBL11640556 | 0.73 | MAOB (0.46) | MAOBADAM17BCHETACR1HTR1A | |
| SCHEMBL9183766 | 0.73 | ALOX5 (0.55) | MAOBADAM17ALOX5 | |
| SCHEMBL9185169 | 0.71 | MAOB (0.47) | MAOBADAM17ALOX5 | |
| SCHEMBL8246377 | 0.71 | OPRM1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137331-A2 | 4-FLUORO-4-ARYLPIPERDIN-1-YL DERIVATIVES AS MU OPIOID FUNCTION MODERATORS | KINENTIA BIOSCIENCES LLC (US) | 2011-11-03 | — | — | WO | disclosed |