Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604635 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2RECQLALDH1A1MAPK1POLB | |
| SCHEMBL25604491 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2RECQLGAAALDH1A1MAPK1 | |
| SCHEMBL25604265 | 0.74 | L3MBTL1 (0.37) | SMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL25826024 | 0.74 | L3MBTL1 (0.37) | SMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL25825902 | 0.73 | L3MBTL1 (0.39) | SMN1; SMN2RECQLGAAALDH1A1MAPK1 | |
| SCHEMBL25604356 | 0.71 | ESR2 (0.39) | SMN1; SMN2RECQLGAAALDH1A1POLB | |
| SCHEMBL11791757 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2RECQLGAAALDH1A1MAPK1 | |
| SCHEMBL25604199 | 0.71 | ESR2 (0.43) | SMN1; SMN2RECQLMAPK1MAPT | |
| SCHEMBL25825841 | 0.69 | L3MBTL1 (0.37) | SMN1; SMN2RECQLGAAALDH1A1POLB | |
| SCHEMBL31443713 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2RECQLGAAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |