SCHEMBL25828187

SCHEMBL25828187

O=C(c1ccc(OCC(=O)N(CCO)CCO)cc1)c1ccccc1C(=O)N(CCO)CCO

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
PDK2 Q15119 1/20 0.45
TRPM8 Q7Z2W7 3/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GAA P10253 2/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
HCRTR1 O43613 1/20 0.38
HCRTR2 O43614 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2386648 0.85 POLB (0.64) POLBPDK2TRPM8MEN1KMT2A
SCHEMBL3401575 0.80 AKR1C3 (0.53) GAAMAPTTP53ALDH1A1
SCHEMBL22221533 0.79 POLB (0.62) POLBPDK2TRPM8MEN1KMT2A
SCHEMBL25828116 0.79 POLB (0.61) POLBPDK2TRPM8MEN1KMT2A
SCHEMBL13288123 0.78 POLB (0.54) POLBPDK2TRPM8MEN1KMT2A
SCHEMBL12998150 0.78 MEN1 (0.57) POLBTRPM8MEN1KMT2AGAA
SCHEMBL4089780 0.75 TP53 (0.67) MEN1KMT2AMAPTTP53SMN1; SMN2
SCHEMBL25829502 0.73 POLB (0.61) POLBPDK2MEN1KMT2ARAB9A
SCHEMBL13159354 0.72 TDP1 (0.42) GAATP53SMN1; SMN2ALDH1A1LMNA
SCHEMBL25828205 0.71 POLB (0.59) POLBPDK2TRPM8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed