Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26317020 | 0.73 | POLB (0.57) | ALDH1A1LMNACYP1A2CYP3A4MAPK1 | |
| SCHEMBL24010781 | 0.72 | DOT1L (0.63) | APPIP6K1EGFRPDGFRBPDGFRA | |
| SCHEMBL25820098 | 0.72 | IP6K1 (0.41) | APPIP6K1EGFRPDE3BPDE3A | |
| SCHEMBL12240676 | 0.71 | IP6K1 (0.50) | APPIP6K1EGFRPDE3BPDE3A | |
| SCHEMBL24003870 | 0.67 | DOT1L (0.50) | APPPDGFRBPDGFRAPDE3BPDE3A | |
| SCHEMBL182841 | 0.66 | LMNA (0.49) | APPEGFRDOT1LMEN1ALDH1A1 | |
| SCHEMBL11625141 | 0.64 | IP6K1 (0.49) | APPIP6K1EGFRPDE3BPDE3A | |
| SCHEMBL20733069 | 0.64 | CYP1A2 (0.51) | APPPDGFRBPDGFRAMEN1ALDH1A1 | |
| SCHEMBL6386612 | 0.64 | IP6K1 (0.42) | IP6K1EGFRPDE3BPDE3AMEN1 | |
| SCHEMBL24003975 | 0.64 | DOT1L (0.50) | APPIP6K1EGFRPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | APP 3796/4885IP6K1 186/4885EGFR 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.