Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121862 | 0.88 | TSHR (0.58) | TSPOALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL25132132 | 0.87 | TSHR (0.53) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL29234164 | 0.87 | LPAR1 (0.48) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL25299417 | 0.82 | POLB (0.49) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL10893742 | 0.82 | TSPO (0.52) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL13319148 | 0.81 | TSPO (0.51) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL25828708 | 0.79 | MEN1 (0.54) | TSPOALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL25296380 | 0.79 | TSPO (0.46) | TSPOLPAR1LPAR5ALDH1A1HTT | |
| SCHEMBL12182366 | 0.76 | SMN1; SMN2 (0.73) | TSPOALDH1A1HTTSMN1; SMN2BCHE | |
| SCHEMBL26025186 | 0.76 | ALDH1A1 (0.52) | TSPOALDH1A1HTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018471-A9 | PIPERAZINE-BASED AGONISTS OF LFA-1 AND VLA-4 | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |