Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121862 | 0.91 | TSHR (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29234307 | 0.87 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10893742 | 0.85 | TSPO (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL25250231 | 0.84 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL24343470 | 0.84 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13319148 | 0.84 | TSPO (0.51) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12182366 | 0.80 | SMN1; SMN2 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL25828611 | 0.79 | TSPO (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6121816 | 0.79 | TSHR (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL24343330 | 0.79 | CALM1 (0.52) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018471-A9 | PIPERAZINE-BASED AGONISTS OF LFA-1 AND VLA-4 | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |