Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250241 | 0.95 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25735584 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL18425498 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2MAPTLMNATRPA1ALDH1A1 | |
| SCHEMBL22590669 | 0.88 | ALDH1A1 (0.46) | SMN1; SMN2MAPTLMNATRPA1ALDH1A1 | |
| SCHEMBL22590668 | 0.88 | PHGDH (0.46) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25735562 | 0.87 | HPGD (0.46) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25280179 | 0.85 | HPGD (0.46) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25828151 | 0.83 | TRPA1 (0.46) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25251886 | 0.82 | HPGD (0.44) | SMN1; SMN2MAPTLMNAHTTTRPA1 | |
| SCHEMBL25828656 | 0.82 | NMT1 (0.44) | LMNAHTTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201928-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-06-28 | — | — | EP | disclosed |