Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523682 | 0.82 | KDM4E (0.62) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL2519345 | 0.79 | KDM4E (0.72) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL2516006 | 0.78 | PAX8 (0.69) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL2519523 | 0.78 | PAX8 (0.69) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL5594514 | 0.74 | KDM4E (0.64) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL31237495 | 0.74 | KDM4E (0.79) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL9177673 | 0.74 | KDM4E (0.79) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL30159468 | 0.74 | KDM4E (1.00) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL1782934 | 0.74 | KDM4E (1.00) | PAX8KDM4EL3MBTL1HTTNPC1 | |
| SCHEMBL30122537 | 0.74 | MAOA (0.61) | PAX8KDM4EL3MBTL1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382193-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | Biopharmed (FR) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010073235-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | BIOPHARMED (FR) | 2010-07-01 | — | — | WO | disclosed |