Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HK1 | P19367 | 1/20 | 0.55 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196215 | 0.81 | MAPT (0.58) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL22822212 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL3140270 | 0.77 | SMN1; SMN2 (0.65) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL25735674 | 0.77 | HTT (0.76) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL7874987 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL28490658 | 0.74 | MAPT (0.58) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL4636395 | 0.74 | TSHR (0.72) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL1399840 | 0.73 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL7121746 | 0.71 | HDAC3 (0.63) | ALDH1A1MEN1KMT2AHPGDHTT | |
| Chlorobenzene SCHEMBL19118520 | 0.71 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201928-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-06-28 | — | — | EP | disclosed |