Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | JAK3 | P52333 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HK1 | P19367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140270 | 0.83 | SMN1; SMN2 (0.65) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL28484582 | 0.79 | JAK3 (0.64) | MAPTALDH1A1HTTLMNAJAK3 | |
| SCHEMBL16404007 | 0.79 | MAPT (0.56) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL7874987 | 0.77 | ALDH1A1 (0.53) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL7121746 | 0.77 | HDAC3 (0.63) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL4003283 | 0.74 | MITF (0.72) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL25829360 | 0.74 | ALDH1A1 (0.59) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL14317625 | 0.74 | MAPT (0.56) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL8057745 | 0.74 | MAPT (0.68) | MAPTALDH1A1HTTLMNARAB9A | |
| SCHEMBL22822212 | 0.74 | ALDH1A1 (0.65) | MAPTALDH1A1HTTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456280-B | 4-phenylthiazole-2-amine derivative containing urea structure and preparation method and application thereof | 锦州医科大学 | 2020-11-10 | — | — | CN | claimed |
| CN-109456280-B | 4-phenylthiazole-2-amine derivative containing urea structure and preparation method and application thereof | 锦州医科大学 | 2020-11-10 | — | — | CN | disclosed |