Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22793715 | 0.86 | ALDH1A1 (0.45) | CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL25784040 | 0.85 | HSD17B1 (0.43) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25784021 | 0.84 | ESR1 (0.44) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21940406 | 0.82 | ABCG2 (0.45) | CYP1A2ALDH1A1HSD17B10CYP1A1FYN | |
| SCHEMBL22420029 | 0.82 | PGR (0.39) | ESR1ESR2CDK4CCND1CYP1A2 | |
| SCHEMBL25829772 | 0.82 | ESR1 (0.38) | ESR1ESR2CDK4CCND1CYP1A2 | |
| SCHEMBL24178696 | 0.82 | ESR1 (0.35) | ESR1ESR2CDK4CCND1CYP1A2 | |
| SCHEMBL25494438 | 0.81 | ABCG2 (0.44) | CYP1A2ALDH1A1HSD17B10CYP1A1FYN | |
| SCHEMBL29330267 | 0.81 | HSD17B1 (0.47) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25927503 | 0.80 | ESR1 (0.48) | ESR1ESR2CYP1A2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | H1-0, H1-2, H1-4 | ESR1 144/4885ESR2 913/4885CDK4 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.