SCHEMBL25829494

SCHEMBL25829494

CCOC(=O)COc1cc(OCC)ccc1C(=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.73
POLB P06746 2/20 0.59
MAPT P10636 3/20 0.52
MAPK1 P28482 2/20 0.52
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KDM4E B2RXH2 5/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
CASP3 P42574 1/20 0.51
CASP7 P55210 1/20 0.51
CASP9 P55211 1/20 0.51
ALDH1A1 P00352 5/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GAA P10253 1/20 0.51
HCRTR1 O43613 1/20 0.48
HCRTR2 O43614 1/20 0.48
ABCB1 P08183 1/20 0.48
ELANE P08246 1/20 0.48
CYP1A2 P05177 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25306124 0.96 HPGD (0.79) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL31006408 0.96 HPGD (0.79) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL16090169 0.88 POLB (0.63) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL9574081 0.85 HPGD (1.00) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL11575792 0.81 MAPK1 (0.63) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL25829502 0.81 POLB (0.61) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL29091884 0.80 POLB (0.53) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL9064154 0.79 HPGD (0.69) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL16092725 0.79 MEN1 (0.61) HPGDPOLBMAPTMAPK1LMNA
SCHEMBL29415022 0.79 KDM4E (0.64) HPGDPOLBMAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed