Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25829889 | 0.86 | MEN1 (0.43) | ALDH1A1LMNAPKMHPGDTSHR | |
| SCHEMBL25014618 | 0.78 | MMP1 (0.41) | ALDH1A1LMNAPKMHPGDTSHR | |
| SCHEMBL21962906 | 0.77 | MMP1 (0.49) | RAB9AMMP1MMP2MMP3PDE4A | |
| SCHEMBL21962930 | 0.73 | MEN1 (0.53) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL22010636 | 0.71 | F2 (0.39) | POLBCA12CA9CA2 | |
| SCHEMBL22010524 | 0.70 | KMT2A (0.46) | MEN1KMT2APOLBCA12CA7 | |
| SCHEMBL22010522 | 0.67 | POLB (0.39) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL25014625 | 0.67 | ABCB1 (0.38) | ALDH1A1LMNAPKMHPGDTSHR | |
| SCHEMBL12268065 | 0.66 | MMP8 (0.46) | ALDH1A1LMNATSHRHSD17B10TP53 | |
| SCHEMBL9554305 | 0.66 | ITGA4 (0.51) | ALDH1A1LMNAPKMHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |