SCHEMBL25830482

SCHEMBL25830482

CN(CCOCCN(CCOCCN(C)C(=O)OC(C)(C)C)C(=O)N1CCN(OC(=O)c2ccccc2)CC1)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
PDK2 Q15119 1/20 0.35
GBA1 P04062 1/20 0.34
HTR2C P28335 2/20 0.34
SLC6A4 P31645 2/20 0.34
USP30 Q70CQ3 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HRH3 Q9Y5N1 2/20 0.32
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25830519 0.75 HPGD (0.32) PDK2
SCHEMBL8695092 0.73 KDM4E (0.52) GBA1USP30KDM4EPKM
SCHEMBL25811526 0.70 USP30 (0.39) CYP1A2CYP2D6CYP2C19USP30KDM4E
SCHEMBL25830559 0.69 MEN1 (0.31)
SCHEMBL1067976 0.69 TDP1 (0.55) CYP1A2CYP2D6CYP2C19PDK2GBA1
SCHEMBL26427726 0.69 POLB (0.42) CYP1A2CYP2D6CYP2C19KDM4ENPSR1
SCHEMBL16993182 0.69 L3MBTL1 (0.62) PDK2GBA1HTR2CSLC6A4L3MBTL1
SCHEMBL2245966 0.68 AKT1 (0.48) PDK2HTR2CSLC6A4L3MBTL1
SCHEMBL25829780 0.68 L3MBTL1 (0.46) PDK2HTR2CSLC6A4L3MBTL1
SCHEMBL16941150 0.68 DRD2 (0.54) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125806-A1 CONJUGATE FOR PREVENTING AND TREATING VIRAL INFECTIONS AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed