SCHEMBL25830871

SCHEMBL25830871

C=CC(=O)OCc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.46
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
PTGES O14684 1/20 0.41
ALOX5 P09917 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HCAR2 Q8TDS4 1/20 0.40
TGM2 P21980 1/20 0.40
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
NAAA Q02083 2/20 0.39
LMNA P02545 2/20 0.39
THRB P10828 1/20 0.39
P2RX4 Q99571 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12727904 0.97 MMP12 (0.43) MMP12KEAP1NFE2L2PTGESALOX5
SCHEMBL13937443 0.95 THRB (0.39) MMP12KEAP1NFE2L2NPC1RAB9A
SCHEMBL22920936 0.95 THRB (0.39) MMP12KEAP1NFE2L2NPC1RAB9A
SCHEMBL11938794 0.94 HCAR2 (0.43) MMP12NPC1RAB9AHCAR2TGM2
SCHEMBL13778858 0.94 HCAR2 (0.45) PTGESALOX5MEN1KMT2ANPC1
SCHEMBL172480 0.94 HCAR2 (0.45) PTGESALOX5MEN1KMT2ANPC1
SCHEMBL9915733 0.92 HCAR2 (0.44) PTGESALOX5MEN1KMT2ANPC1
SCHEMBL13777455 0.91 HCAR2 (0.45) KMT2ANPC1RAB9AHCAR2TGM2
SCHEMBL16625916 0.91 HCAR2 (0.45) KMT2ANPC1RAB9AHCAR2TGM2
SCHEMBL12534114 0.91 HCAR2 (0.45) KMT2ANPC1RAB9AHCAR2TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed