SCHEMBL25830897

SCHEMBL25830897

C=CC(=O)OCCOc1ccc(-c2ccc(N(c3ccccc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.61
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
FFAR4 Q5NUL3 2/20 0.41
FFAR1 O14842 1/20 0.41
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 2/20 0.39
HTT P42858 1/20 0.39
PTGER4 P35408 1/20 0.39
KDM4E B2RXH2 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
MCL1 Q07820 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
RARB P10826 1/20 0.38
TP53 P04637 1/20 0.38
PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13854044 0.95 THRB (0.56) THRBATML3MBTL1FFAR4NPC1
SCHEMBL25830880 0.94 THRB (0.69) THRBRAB9ANPC1KMT2AMEN1
SCHEMBL19601496 0.92 THRB (0.52) THRBATML3MBTL1FFAR4KMT2A
SCHEMBL26532006 0.92 THRB (0.52) THRBATML3MBTL1FFAR4KMT2A
SCHEMBL20086240 0.92 THRB (0.69) THRBRAB9ANPC1KMT2AMEN1
SCHEMBL14179115 0.92 THRB (0.60) THRBL3MBTL1NPC1KMT2AMEN1
SCHEMBL16625918 0.91 THRB (0.56) THRBL3MBTL1FFAR4RAB9ANPC1
SCHEMBL25830904 0.90 THRB (0.75) THRBL3MBTL1FFAR1RAB9ANPC1
SCHEMBL14195319 0.90 THRB (0.54) THRBATML3MBTL1FFAR4FFAR1
SCHEMBL19601508 0.89 THRB (0.48) THRBL3MBTL1FFAR4NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed