SCHEMBL16625918

SCHEMBL16625918

C=CC(=O)OCCOc1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc(N(c5cccc(C)c5)c5cccc(C)c5)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
LTB4R2 Q9NPC1 2/20 0.43
PTGER4 P35408 1/20 0.39
FFAR4 Q5NUL3 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
PPARG P37231 4/20 0.37
PPARA Q07869 2/20 0.37
PPARD Q03181 1/20 0.37
LTB4R Q15722 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19229848 0.95 THRB (0.49) THRBL3MBTL1TDP1LTB4R2FFAR4
SCHEMBL25830897 0.91 THRB (0.61) THRBL3MBTL1PTGER4FFAR4NPC1
SCHEMBL25830880 0.90 THRB (0.69) THRBNPC1RAB9ALMNA
SCHEMBL20086240 0.88 THRB (0.69) THRBPTGER4NPC1RAB9A
SCHEMBL13854044 0.86 THRB (0.56) THRBL3MBTL1FFAR4NPC1MAPK1
SCHEMBL25830904 0.86 THRB (0.75) THRBL3MBTL1NPC1RAB9ALMNA
SCHEMBL13569469 0.86 ALOX5 (0.40) THRBLTB4R2
SCHEMBL9915730 0.85 THRB (0.42) THRBTDP1LTB4R2NPC1RAB9A
SCHEMBL9915683 0.85 THRB (0.42) THRBTDP1LTB4R2NPC1RAB9A
SCHEMBL12234087 0.85 THRB (0.42) THRBTDP1LTB4R2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500967-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-9500967-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-20150099218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-09 US disclosed
US-20150099218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-09 US disclosed