SCHEMBL25830904

SCHEMBL25830904

C=CC(=O)OCCOc1ccc(N(c2ccccc2)c2ccc(OCCOC(=O)C=C)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.75
PKM P14618 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
TSHR P16473 5/20 0.42
HPGD P15428 2/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
ALDH1A1 P00352 6/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 2/20 0.42
PARP10 Q53GL7 1/20 0.42
LMNA P02545 1/20 0.41
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25830880 0.96 THRB (0.69) THRBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL20086240 0.93 THRB (0.69) THRBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL25830897 0.90 THRB (0.61) THRBMEN1KMT2AKDM4ETSHR
SCHEMBL9970457 0.89 THRB (0.59) THRBTSHRHPGDRAB9ANPC1
SCHEMBL1624075 0.89 THRB (0.68) THRBSMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL21865709 0.87 THRB (0.60) THRBSMN1; SMN2MEN1KMT2ATSHR
SCHEMBL14179115 0.87 THRB (0.60) THRBMEN1KMT2ATSHRHPGD
SCHEMBL16625918 0.86 THRB (0.56) THRBRAB9ANPC1LMNAPPARG
SCHEMBL34035 0.86 THRB (1.00) THRBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL28230342 0.86 THRB (1.00) THRBPKMSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20240027928-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-25 US disclosed
US-20240027928-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-25 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed