Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.31 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830922 | 0.92 | STING1 (0.37) | STING1TP53MAPT | |
| SCHEMBL25807890 | 0.83 | STING1 (0.48) | STING1TP53MAPTUSP28USP25 | |
| SCHEMBL25830940 | 0.78 | STING1 (0.49) | STING1TP53MAPT | |
| SCHEMBL30563377 | 0.76 | STING1 (0.47) | STING1TP53MAPTUSP28USP25 | |
| SCHEMBL25807112 | 0.68 | RIPK1 (0.47) | — | |
| SCHEMBL25830558 | 0.67 | STING1 (0.68) | STING1TP53MAPT | |
| SCHEMBL21710332 | 0.65 | USP28 (0.50) | USP28USP25 | |
| SCHEMBL25830557 | 0.65 | STING1 (0.63) | STING1TP53MAPT | |
| SCHEMBL30563397 | 0.64 | USP28 (0.30) | USP28USP25 | |
| SCHEMBL21710325 | 0.64 | USP25 (0.48) | USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |