SCHEMBL25831011

SCHEMBL25831011

C=CC(C)OCc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(CCC)cc3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.33
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
CNR2 P34972 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
AGXT P21549 2/20 0.31
NR1H4 Q96RI1 1/20 0.30
NISCH Q9Y2I1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15681410 0.79 LPL (0.44) CNR2ESR1ESR2NISCH
SCHEMBL25830855 0.77 THRB (0.50) THRBESR1ESR2
SCHEMBL12751481 0.74 AGXT (0.37) CNR2AGXT
SCHEMBL279004 0.74 AGXT (0.37) PPARGPPARAAGXT
SCHEMBL14981808 0.74 LPL (0.48) CNR2ESR1ESR2
SCHEMBL973801 0.74 LPL (0.48) CNR2ESR1ESR2
SCHEMBL14541795 0.74 AGXT (0.39) CNR2AGXT
SCHEMBL13422649 0.73 RARB (0.47) CNR2NISCH
SCHEMBL15681407 0.73 CNR2 (0.49) CNR2
SCHEMBL17321116 0.73 MAOB (0.51) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed