SCHEMBL25830855

SCHEMBL25830855

C=CC(=O)OCc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(CCC)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.50
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MCL1 Q07820 1/20 0.36
NAAA Q02083 1/20 0.36
MMP12 P39900 1/20 0.35
TGM2 P21980 1/20 0.35
THRA P10827 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532016 0.95 THRB (0.55) THRBESR1ESR2MCL1NAAA
SCHEMBL13937443 0.94 THRB (0.39) THRBMMP12TGM2
SCHEMBL22920936 0.94 THRB (0.39) THRBMMP12TGM2
SCHEMBL13840012 0.91 THRB (0.46) THRBMMP12TGM2THRA
SCHEMBL25830902 0.90 THRB (0.50) THRBESR1ESR2MCL1MMP12
SCHEMBL11987082 0.90 THRB (0.42) THRBMMP12TGM2
SCHEMBL2602454 0.90 THRB (0.42) THRBMMP12TGM2
SCHEMBL12727904 0.89 MMP12 (0.43) THRBMMP12TGM2
SCHEMBL25830871 0.89 MMP12 (0.46) THRBNAAAMMP12TGM2
SCHEMBL13839907 0.88 THRB (0.43) THRBMMP12TGM2THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230324818-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCING METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2023-10-12 US disclosed
US-20230324818-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCING METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2023-10-12 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed