Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508124 | 0.82 | — | — | |
| SCHEMBL4508130 | 0.82 | — | — | |
| SCHEMBL2585015 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL2578450 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTTDP1DPP4MAPT | |
| SCHEMBL2585115 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1DPP4GAA | |
| SCHEMBL22040222 | 0.77 | NR3C2 (0.43) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL2585920 | 0.74 | XPO1 (0.39) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL2344446 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL2344442 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL20835448 | 0.74 | RAB9A (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |